Centennial is a home rule municipality located in Arapahoe County, Colorado, United States.

Centennial was formed on February 7, 2001, from portions of unincorporated Arapahoe County, including the former Castlewood and Southglenn census-designated places (CDPs).

(One of the campaigns against incorporation appealed to voters to maintain the 3.8% sales tax of the unincorporated county.)

Centennial is roughly divided in half by Interstate 25, with most of its business and entertainment centers lying west of the highway.

Centennial hosts most native wildlife and is a good reflection of Colorado's front range ecosystem.

According to Centennial's 2023 Annual Comprehensive Financial Report,[14] the top employers in the city are: Most of Centennial is within the territory of the Cherry Creek Public Schools while the western portion of the city in the territory of Littleton Public Schools.