It was founded by Tatsuji Nomura in 1952 with the mission of improving the level of biomedical research.

ICLAS Monitoring Center was established in the CIEA in 1979 and is the only center in the world for testing and verifying the quality of laboratory animals, under the direction of Dr. Tatsuji Nomura with a conduct of International Council for Laboratory Animal Science (ICLAS).

The Monitoring Center program came on the agenda in ICLAS early in the 1970s and the goal was set to assist the scientific bodies in finding animals of the highest quality.

At that time, the planning of an ICLAS Monitoring Center System and the preparation of an International Manual on Genetic Monitoring, which had been in development for some time, was progressing well.

The final proposal was later approved by the Board as a realistic and well-founded scheme that would give the users of laboratory animals a far better program and would help re-establish confidence in the system.