USHS is not included in the Philippine Science High School System and is under the College of Education of the Central Luzon State University.

1622 dated June 14, 1976 as a prime school for students who want to pursue science and technology courses which the country needs for its massive and sustaining development programs.

The school has opened its doors to interested applicants who qualify through screening by an entrance examination to fill up the limited slot of 80 in the first year level since 1978.

[3] The curriculum includes courses that cover the basic concepts of biology, chemistry, physics, mathematics, computer science, English, Filipino, social studies, and the arts.

The school also offers a number of extracurricular activities that allow students to explore their interests, develop their skills, and work with others.