The University Junior High School was established in 1913 eight years after the Jaro Industrial School, the Central Philippine University's precursor established, by William Orison Valentine, an American missionary working under the auspices of the American Baptist Foreign Mission Society.

The CPU Junior High School has an adequate educational facilities in accordance with its continued vision as a modern junior secondary education school grounded on Christian and scientific teachings.

The junior high school compound is composed of the 3 storey CPUJHS Main Building interconnected to a two and one storey structures which houses primarily the school's lecture rooms for Physical Education, Social Sciences, Mathematics, Filipino, English, Statistics, and Values Education.

Part of the structure includes the principal's office, faculty rooms, junior high school speech laboratory, computer laboratory and the Junior High School Library, the CPUJHS Guidance and Counseling Center, the junior secondary education departmental library of the CPU Library System; the two storey CPUJHS Science Building (formerly CPUHS Science and H.E.

The school has produced thousands of graduates since it was established in 1913 as an organics secondary education unit of the university.