[9] A 14-year-old female student committed suicide in February 2023 after videos of her being physically attacked in a hallway of the school surfaced online.

The student's father believes that public humiliation and continued online bullying after this event spurred his daughter to end her own life.

[21] The 1984 baseball team, led by Al Leiter, finished the season with a record of 25-5-1 after winning the Group III state championship by defeating Indian Hills High School by a score of 8-1 in the tournament final.

[24] The softball team defeated Paramus High School in the final of the playoffs to win the 1996 Group III state championship.

The Eagles were Class B-South co-champions in 1988, defeating arch-rival and state champion Lacey Township High School, 18-15.

The Central Regional boys' soccer program is coached by Troy Van Hise, Robert Bechtloff, and Cody Ertle.

The girls' soccer program at Central is led by Meredith Parliman, who is assisted by Lauren Stoltzfus and Brianne Toomey.

In 1973, Mike Baeli became the first wrestler to win a match at the state level, finishing fourth after defeating Art Kubo in the first round.

In 1985, Central Regional crowned its first NJSIAA state champion, the late Darnell Myers, under the guidance of coach Paul Mueller.

)[27] Maurice went on to a runner-up finish in the NCAA Division I Championships while attending the United States Military Academy at West Point.

In 2005, the team won its first ever South Jersey Group III State Sectional title in thrilling fashion over four-time defending champion Kingsway Regional High School.

[28] The following season brought a second South Jersey Group III title after dispatching Kingsway for the second straight year, taking five of the final six matches to win 34-27.