Centre for Excellence in Basic Sciences (Hindi: मौलिक विज्ञान प्रकर्ष केंद्र) (or UM-DAE CEBS) is an autonomous institute with an affiliation to the University of Mumbai.

The Institute was inaugurated on 17 September 2007 by Dr R. Chidambaram, Principal Scientific Advisor to the Government of India.

Currently, CEBS students are housed in the Takshashila building near Nalanda and Pre-Fab rooms near Annabhau Sathe Bhavan.

Admission to PhD degree is offered in all four subjects Biology, Chemistry, Mathematics and Physics.

The institute at present has 4 departments which are: Various research works are being carried out at CEBS in close association with institutes like TIFR, BARC, Institute of Chemical Technology (UDCT) in nuclear physics, astrophysics, free electron lasers, biophysics, genetics, chemical biology, cell and developmental biology, and cancer biology and therapeutics.

Students of UM-DAE CEBS, known as CBScients, reside at Takshashila building and pre-fabricated housing structures in the Kalina campus if the Mumbai University.

In addition, students can use the sports facilities provided by CEBS as well as the Bombay University.