The center of Chadds Ford village constitutes the Chadds Ford Historic District, listed on the National Register of Historic Places.

The Battle of Brandywine occurred at Chadds Ford during the American Revolutionary War.

Other points of interest in the CDP include the Brandywine River Museum of Art, showcasing the work of the Wyeth family; the Christian C. Sanderson Museum; Painter's Folly, the summer residence of Howard Pyle; and the Chaddsford Winery.

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