Milford Mills was a village that was located in the Marsh Creek Valley of Chester County, Pennsylvania, United States.

Milford Mills was one of several farming villages that were settled in Upper Uwchlan Township by Welsh, Scots-Irish and English during the first quarter of the eighteenth century.

Later bypassed by large-scale industry, the region reverted to an agricultural economy until after World War II when the Pennsylvania Turnpike brought suburban development to northwestern Chester County.

[3] Despite protests from some residents, the Commonwealth of Pennsylvania acquired thirty-four properties throughout the region for the project, razing the village and nearby woodlands.

Abandoned roads and traces of houses, barns and other structures can be seen on the shores of the lake and in adjacent recreation areas in Marsh Creek State Park.