A variety of important biological compounds are known collectively as chalcones or chalconoids.

[3] They are widely known bioactive substances, fluorescent materials, and chemical intermediates.

The enzyme is found in all "higher" (vascular) and several "lower" (non-vascular) plants.

[6] This reaction, which can be carried out without any solvent, is so reliable that it is often given as an example of green chemistry in undergraduate education.

[7] Chalcones and their derivatives demonstrate a wide range of biological activities including anti-inflammation.