The community is divided in two parts, Chorio (Χωριό, also spelled Horio, "Village") and Emporio (Εμποριό, "Market").

A sizable group of the residents moved to Tarpon Springs, Florida, establishing the Greek-American community there that continues to this day.

A ruined medieval castle of the Knights of St. John overlooks the old town and the chapel contains some of the original frescoes.

The Municipality of Chalki includes several uninhabited offshore islands, the largest of which is Alimia to the northeast, and has a total land area of 37.043 square kilometres (14.302 sq mi).

This initiative is anticipated to diminish the island's carbon footprint, reducing CO2 emissions by an estimated 2,576 tonnes.