Note that an ion channel may overlap between different categories.
Examples of targets for modulators include: Voltage-gated ion channels
For lists of the substances that pharmacologically modulate them, see their respective articles.
For example with G protein coupled receptors (GPCRs), for G protein coupled inward rectifier potassium channels (GIRKs) and M channels.
Ion channels can also be modulated by reuptake inhibitors and releasing agents.