Charles Edward Roesch (March 31, 1886 – January 15, 1936) was Mayor of the City of Buffalo, New York, serving from 1930 until 1933.

He was born in Buffalo at 613 Oak Street on March 31, 1886, the son of a leading local meatpacker.

The Roesch's lived at one address for their entire marriage, 633 North Oak Street, just down the block from where he was born.

During his term the country was in the throes of the Great Depression and Roesch was a leader and innovator in the relief programs for the unemployed.

His grandson, Charles W. Roesch, continues to run the family business under the name Charlie the Butcher.