Francis Xavier Schwab (August 14, 1874 – April 23, 1946) was Mayor of the City of Buffalo, New York, serving from 1922 until 1929.

"By this time, Frank Schwab had developed a personal style that delighted his friends and infuriated his enemies".

But in 1921, as a joke the Knights of St. John circulated a petition on behalf of Schwab for his mayoral candidacy.

During his term, in the summer of 1922, the last and most bitter street railway strike occurred; Schwab declared a transportation emergency and authorized the running of buses.

In 1923–1924, the city purchased land for an airfield and, on September 27, 1926, Mayor Schwab laid the cornerstone of the administration building for the Buffalo Airport.