Charles Hudson Griffin (May 9, 1926 – September 10, 1989) was an American World War II veteran and politician who served as a member of the United States House of Representatives from Mississippi's 3rd congressional district from 1968 to 1973.

He attended Utica High School and Hinds Community College before graduating from Mississippi State University in 1949.

He served in the United States Navy from 1944 to 1946 in Pacific War as a third class apprentice seaman and quartermaster.

Griffin served as assistant to United States Representative John Bell Williams from July 1, 1949, to January 15, 1968.

Griffin was elected as a Democrat to the Ninetieth Congress in a special election triggered by Williams' successful bid for governor of Mississippi.