His third novel, Star Wars: Light of the Jedi, was released by Del Rey Books on January 6, 2021, debuting at #1 on the New York Times bestseller list.

[1][2] Charles Soule attended the University of Pennsylvania,[3] where he received his undergraduate degree in Asian and Middle Eastern Studies, with a concentration in Chinese language and history.

His other creator-owned projects include Strange Attractors, about complexity theory applied to New York City by two genius mathematicians, released by Archaia in May 2013, and Letter 44, from Oni Press, a real-world sci-fi political thriller involving a crewed space mission to investigate an anomaly in the asteroid belt.

In January 2016, Soule was announced as the writer of a Marvel ongoing series focusing on the Poe Dameron character from Star Wars: The Force Awakens, with Phil Noto as artist.

In January 2018 it was reported that Soule would be writing a miniseries titled Hunt for Wolverine, which would span multiple genres in exploring the mystery behind the character's return from the dead in 2017's Marvel Legacy #1.

[2] In June 2022, it was announced that Amazon Studios had picked up the rights to make film and television shows based on Eight Billion Genies, with Soule and Ryan Browne set to executive produce.

[25] In October 2024, it was announced that Soule would reunite with Browne for a 9-issue series entitled The Lucky Devils for Image Comics, with the first issue set to debut in January 2025.

[30] Soule's series Letter 44, illustrated by Alberto Jiménez Alburquerque, was an official selection of the 2016 Festival International de la Bande Dessinée in Angoulême, France, recognizing it as one of the best graphic titles published in the French language in the preceding year.

[32] Soule's series 27: First Set (with Renzo Podesta) was included on the "Great Graphic Novels" list from the Young Adult Library Services Association (YALSA) in 2012.