She was the daughter of Granville Leveson-Gower, 1st Marquess of Stafford, and his wife, the former Lady Susanna Stewart.

[2] She married the future duke, then Marquess of Worcester, on 16 May 1791 at Lambeth Church, London.

They had four sons and eight daughters:[3][4] In 1803, her husband succeeded his father as Duke of Beaufort, and she rose from marchioness to duchess.

The dowager duchess then lived with her youngest daughter at her London home in Grosvenor Square.

She was included in the "Gallery of Beauties" series commissioned by Prince Regent (later King) George IV.