Chile and Mexico both share a common history in that they were both hosts to advanced indigenous societies and were both colonized by Spain.

In 1864, during the Second French intervention in Mexico, Chile recognized and maintained diplomatic relations with the government of President Benito Juárez.

That year, the ABC nations intervened in a diplomatic dispute between the United States and Mexico who were on verge of war over the Tampico Affair and the subsequent occupation of Veracruz by US forces.

During the visit, both leaders discussed the election of a new head for the Inter-American Development Bank and to increase bilateral relations and agreements between both nations.

[6] In September 2023, Mexican President Andrés Manuel López Obrador paid a visit to Chile to commemorate the 50th anniversary since the 1973 Chilean coup d'état.

[21] Chile's main exports to Mexico include: lumber, plywood, salmon, peaches, cheese, wine and copper.

Mexico's main exports to Chile include: automobiles and parts, tractors, electronics, machinery and beer.