Chimmini Wildlife Sanctuary is a protected area located along the Western Ghats in Chalakudy taluk of Thrissur District of Kerala state in India.

Established in 1984, the sanctuary with an area of about 85.067 km2 is on the western slopes of the Nelliyampathi Hills.

Along with the neighboring Peechi-Vazhani Wildlife Sanctuary it forms a continuous protected area of 210 km2.

It also lies just west of Parambikulam Wildlife Sanctuary, providing some habitat connectivity with the forests of that relatively large protected area.

Nestled in the sanctuary is Chimmony Dam which is built across the Chimmini river.