Possible side effects include dizziness, lightheadedness, malaise, nausea, vomiting.
[medical citation needed] In rare cases, chlorzoxazone may cause severe liver dysfunction.
It is believed that metaxalone works by altering serotonin levels and acting as a mild MAO inhibitor.
to act on GABAA and GABAB receptors and voltage-gated calcium channels to a degree.
[medical citation needed] Elucidation of the exact mechanism of action is ongoing but there is limited study due to the existence of more effective, safe muscle relaxants (e.g., diazepam, cyclobenzaprine, tizanidine), greatly limiting the potential benefit of identifying novel compounds which share chlorzoxazone's mechanism of action.