Cardona is the author of the thesis entitled United Nations Commission on International Trade Law – A Maltese Perspective.

Prior to his appointment as Minister for the Economy, Investment and Small Business, Cardona was a senior partner at law firm CV Advocates.

[1] In January 2017, investigative journalist Daphne Caruana Galizia alleged that, while in Germany on official government business, Cardona visited a brothel with his aide Joe Gerada.

Both Cardona and Gerada denied the claims and instituted legal action in the form of libel suits, however before the case was decided in court, Carauna Galizia was killed in a car bomb attack.

[5] The change in Prime Minister to Robert Abela in January 2020 saw Chris Cardona excluded from the position of Minister in the new government, resigning as an MP in April, but continued as Deputy Labour Leader until in June 2020 when Abela asked him to resign due to ongoing police and court revelations regarding the murder of Daphne Caruana Galizia.