Christian Samuel Weiss (26 February 1780 – 1 October 1856) was a German mineralogist born in Leipzig.

Following graduation, he worked as a physics instructor in Leipzig from 1803 until 1808. and in the meantime, conducted geological studies of mountain formations in Tyrol, Switzerland and France (1806–08).

Weiss is credited for creating parameters of modern crystallography, and was instrumental in making it a branch of mathematical science.

He stressed the significance of direction in crystals, considering crystallographic axes to be a possible basis for classification of crystals.

He is credited for introducing the categorization schema of crystal systems, and has a basic law of crystallography named after him called the "Weiss zone law".