In 1958, Christopher Columbus High School was built in an area that was then surrounded by Everglades swampland.

In order to graduate, students require twenty-four credits and a grade point average (GPA) of at least 2.0.

Many Marist Brothers hold positions at Columbus including president, guidance counselors, career and college advisors, and teachers.

Christopher Columbus High School also plays host to both Homecoming and Prom events each year for their students and their dates.

At Columbus, students also compete in non GMAC clubs such as: Roller Hockey, Fishing, Scuba Diving, and Personal Fitness.

Varsity level sports offered are: baseball, basketball, football, volleyball, hockey, soccer, bowling, cross country, golf, lacrosse, swimming, diving, tennis, track and field, water polo and wrestling.

Junior varsity level sports include: baseball, basketball, football, volleyball, hockey, soccer, wrestling and lacrosse.

In 2009, Christopher Columbus High School won the Dodge Sunshine Cup All-Sports Award for boys' athletics programs in Class 6A.

[7] Additionally, Columbus won the Miami Herald's All-Dade Boys' Major Sports Award in 2008[16] and 2009.