[2] Born 1969 in Athens and raised in the nearby Ampelokipoi,[1] Spirtzis studied Electrical engineering at the Democritus University of Thrace.

[1] In 2007, he became vice president responsible for energy, development, employment, insurance, licensing, publications, ethics in representation, and the databank.

[4] Spirtzis, who has been described as a "child" of social-democratic PASOK, however wasn't hesitant to clash with his party, especially in strongly opposing the Memorandum.

[1] After the January 2015 legislative election, Spirtzis was appointed Alternate Minister of Infrastructure, Transport and Networks by the Syriza-led government of Alexis Tsipras.

"[7] In an article published by Politico,[8] Spirtzis was mentioned as one of the two former ministers suspected by EPPO prosecutors for breach of duty in connection with the Tempi train crash in Feb 28 2023 where 57 people were killed.