[1] Okorafor was born in Nigeria, and lived in South Africa and Botswana before his family emigrated to the United States in 2010.

Chukwuma received offers from numerous programs, some of which included Arkansas, Florida, Iowa, Nebraska, North Carolina State, Ohio State, and Oklahoma, but chose to play at Western Michigan due to its close proximity to home and the school's promise to start him as a true freshman.

[18] On November 25, 2018, against the Denver Broncos, Okorafor made his first NFL start at right tackle due to injuries to Marcus Gilbert and Matt Feiler.

[21][22] On November 10, 2019, against the Los Angeles Rams, Okorafor made his first start of the 2019 NFL season due to an injury to Ramon Foster.

[27] He would not return to the team after the five-day exemption period expired, meaning that he would not be allowed to play for the rest of the season.