[2][3] When bitten, humans experience itchiness, wheals, and lesions around the affected areas on the skin.

[4]  This species typically resides in human domiciles within cracks, crevices, or mattresses, and are more prevalent in developing countries.

The rounded, black or red colored compound eyes sit laterally on both sides of the head and can be observed from both a top and underside view.

In accordance to this, the three segmented labium is long and "straw like" and the maxilla and mandible are both observed to be "blade like".

This species has an eight segmented abdomen that is rounded and has a pointed tip, which contains short tufts of hair that stick out.

[6][3] Cimex hemipterus exhibits a hemimetabolous life cycle, which means the insect goes through multiple nymphal life stages, where their body shape and feeding behavior closely resembles that of the adult stage.

This has caused re-emergences of widespread C. hemipterus infestations in countries in the southern hemisphere, such as Australia and Sri Lanka.

These factors act to continue blood flow to the bitten area and ensure the host does not feel the bite.