Even though word of his soda spread over southeastern New England in the next few years, the cost of such fine ingredients eventually forced Henry Millis to sell his company in 1901.

The new proprietors, Horace A. Kimball and his son, H. Earle Kimball, took advantage of every form of advertising, including the character "Kleek-O the Eskimo Boy" (which became a well-known advertising symbol);[2] an animated sign in Manhattan's Times Square (the largest animated sign in the world from 1924 to 1926); and even a musical variety radio program, The Clicquot Club Eskimos, led by banjo player Harry F.

In the 1950s the company began distributing internationally, in places such as Jamaica, Nassau, the Bahamas, virtually all of South America, and the Philippines.

The company began to decline in sales worldwide amid growing competition from other soft drink makers and was purchased in 1969 by the Cott Beverage Corporation of Connecticut.

Today the original plant in Millis remains mostly abandoned, although one-third of it is (as of January 2013) occupied by garden and hardware stores.