[2] The county was created on February 14, 1850, named in honor of Duncan Lamont Clinch.

Eastern and southeastern portions of the county lie within the Okefenokee Swamp and its federally protected areas.

The vast majority of Clinch County is located in the Upper Suwannee River sub-basin of the Suwannee River basin, with just a portion of the western and northwestern edge of the county, southwest and well northwest of Du Pont, located in the Alapaha River sub-basin of the same Suwannee River basin.

[5] As of the 2020 United States census, there were 6,749 people, 2,477 households, and 1,639 families residing in the county.

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