It is endemic[1] to the Madeira River Basin in the states of Amazonas and Rondônia in the central and southwestern Brazilian Amazon.

Again in 1986, an expedition led by the botanist Juan Revilla found and made a photographic record of a very large-leaved but sterile Coccoloba individual near Porto Velho city, in the state of Rondônia; again no herbarium specimen was collected.

Between 1989 and 1993, some 14 individuals were found in several expeditions in Jamari National Forest Reserve; some large leaves were collected even though the specimens were sterile.

Individuals of large-leaved Coccoloba were again photographed by Silvestre Silva in 1995 at a vicinal road connecting the city of Autazes to the left bank of the Madeira River, about 110 km southeast of Manaus.

Finally, an August 2005 expedition in another area in the vicinity of Jamari Forest Reserve led to the collection of fertile samples of inflorescences along with fallen mature fruits and seeds beneath one individual tree.