Coixtlahuaca (Chocho: Nguichee; Mixtec: Yodzocoo; Nahuatl: Coaixtlahuacan) was a pre-Columbian Mesoamerican state in the Mixteca Alta (now in Oaxaca, Mexico).

Coixtlahuaca was a multi-ethnic polity, inhabited by both Chochos and Mixtecs.

In addition to the Chocho and Mixtec languages, Nahuatl was used as a lingua franca.

According to Hernán Cortés, envoys of Coixtlahuaca surrendered to the Spanish in September 1520.

This article related to indigenous Mesoamerican culture is a stub.