Colby High School offers Advanced Placement courses, of which approximately a quarter of the student body takes part in.

[2] For the 2020–21 academic year, Colby High School (Wisconsin) enrolled 305 students, according to the National Center for Education Statistics.

The school employed 18.41 full-time equivalent educators, resulting in a student to teacher ratio of 16.6:1.

The Colby athletic teams are nicknamed the Hornets and compete in the Cloverbelt Conference.

[4] Colby has two competitive show choirs, the mixed-gender Coalition and the women's-only Hornettes.