The Colorado Mesa Mavericks (formerly Mesa State Mavericks) are the athletic teams that represent Colorado Mesa University, located in Grand Junction, Colorado, in NCAA Division II intercollegiate sports.

The Mavericks compete as members of the Rocky Mountain Athletic Conference for all 28 varsity sports.

Beach volleyball is a fully sanctioned NCAA sport which had its first national championship in the spring of 2016.

In addition to varsity sports, CMU has a large number of club sports which include alpine skiing, nordic skiing, cycling, ice hockey, e-sports, rodeo, and women's rugby.

Since 1958, Grand Junction has co-hosted the NJCAA Junior College World Series at Suplizio Field, unassociated to the CMU Athletic Department CMU plays host to several summer sports camps and clinics including baseball, football, cross country, cheerleading, lacrosse, swimming, soccer, track and field, volleyball, and wrestling, as well as the largest summer basketball camp west of the Mississippi River.