All of Colorado's executive offices and all seven of its seats in the United States House of Representatives were up for election.

Democrats swept the statewide offices up for election, leaving the at-large seat on the University of Colorado Board of Regents and the Class 2 U.S. Senate seat as the last statewide offices held by Republicans.

Walker Stapleton Republican Dave Young Democratic Incumbent Republican state treasurer Walker Stapleton was term-limited and could not run for a third consecutive term in office.

Democrats gained two seats and a 19–16 majority, which ended Republican control of the chamber.

All of Colorado's seven seats in the United States House of Representatives were up for election in 2018.