Conidiobolomycosis

Conidiobolomycosis is a rare long-term fungal infection that is typically found just under the skin of the nose, sinuses, cheeks and upper lips.

[4] Typically there is a firm painless swelling which can slowly extend to the nasal bridge and eyes, sometimes causing facial disfigurement.

[6] Most cases are caused by Conidiobolus coronatus, a fungus found in soil and in the environment in general, which can infect healthy people.

[4] It is usually acquired by inhaling the spores of the fungus, but can be by direct infection through a cut in the skin such as an insect bite.

[6] The condition occurs more frequently in adults working or living in the tropical forests of South and Central America, West Africa and Southeast Asia.

[4] The infection presents with firm lumps just under the skin of the nose, sinuses, upper lips, mouth and cheeks.

[6] Infection may extend to involve the nasal bridge, face and eyes, sometimes resulting in facial disfigurement.

[5] The disease is acquired usually by breathing in the spores of the fungus, which then infect the tissue of the nose and paranasal sinuses, from where it slowly spreads.

[6] The disease is rare, occurring mainly in those working or living in the tropical forests of West Africa, Southeast Asia, South and Central America,[4] as well India, Saudi Arabia and Oman.

[9] Affected mammals typically present with irregular lumps in one or both nostrils that cause obstruction, bloody nasal discharge and noisy abnormal breathing.