Majocchi's granuloma is a skin condition characterized by deep, pustular plaques, and is a form of tinea corporis.

Firm or fluctuant subcutaneous nodules or abscesses represent a second form of MG that is generally observed in immunosuppressed hosts.

Lesions start as solitary or multiple well-circumscribed perifollicular papulopustules and nodules with or without background erythema and scaling.

Unlike traditional tinea corporis (commonly known as ringworm) that resides in the top layer of the skin, Majocchi's granuloma contains dermatophytes that invade the hair follicle and/or dermis.

Physical factors that play a major role in inhibiting dermal invasion include the interaction among keratin production, the rate of epidermal turnover, the degree of hydration and lipid composition of the stratum corneum, CO2 levels, and the presence or absence of hair.

These fungi are keratinophilic and colonize or infect the superficial keratinized tissues (the skin, nails, and hair) of humans and animals.

The fungi are usually unable to penetrate into viable tissues in an immunocompetent host and therefore the infection incidence is higher in immune compromised individuals.

This pathological examination of the skin biopsy helps to arrive at the correct diagnosis via a fungal culture (mycology).

Historical therapies include oral potassium iodide, mildly filtered local X-radiation, and topical applications of Asterol as a fungicide in both tincture and ointment forms.

[5] The review article, "Majocchi’s granuloma: a symptom complex caused by fungal pathogens"[8] concludes that the Tzanck smear method is a rapid and easy diagnostic test.

[citation needed] The article "Tinea Corporis Gladiatorum Presenting as a Majocchi Granuloma"[9] discussed the importance of differential diagnosis.

It includes a case report involving a 20-year-old male H who had been a part of schools wrestling team for the past six years.