[2] The constitutional amendment to create the county was proposed July 30, 1918, and ratified November 5, 1918.

It is named for former Civil War general Philip Cook of the Confederate States Army.

[3] Reed Bingham State Park is in Cook County.

[4] The western half of Cook County, located roughly west of Interstate 75, is located in the Little River sub-basin of the Suwannee River basin.

[5] As of the 2020 United States census, there were 17,229 people, 6,217 households, and 4,243 families residing in the county.