Reyer began her career with runway modeling for various shows in Europe, such as Yves Saint Laurent and Helmut Lang.

She expressed an interest in modeling in the United States, and contacted an American agency through her hairstylist at the time, Peter Savic.

Reyer became a regular fixture at numerous runway shows, including Dolce & Gabbana, Prada, Comme des Garçons, Jil Sander, Max Mara, Thierry Mugler, and Bottega Veneta.

[1] Reyer's most high-profile advertising campaign was for American cosmetic company Revlon in the famous "Unforgettable Women" series photographed by Richard Avedon.

[2] Reyer also modeled for Adrienne Vittadini, Anne Kleinlein, Bloomingdale's, DKNY, Eddie Bauer, Enrico Coveri, Gap, Iceberg, and Katharine Hamnett ads.