Two panels of the predella which once was part of the work are known; they portray the Marriage and the Funeral of the Virgin, and are currently exhibited in the museum of San Marco, Florence.

It portrays Christ crowning the Virgin; both are surrounded by rays (executed through an engraving technique above the gilded background) which symbolize the divine light.

The painting has a mystic tone found in other Fra Angelico works, with a large crowd of saints, angels and blessed figures enhancing this aspect.

His face is perhaps modelled on that of Antonino Pierozzi, the former prior of the convent of San Marco to which Fra Angelico belonged.

The structure of the work and the use of brilliant colors shows the influence of Angelico's master, Lorenzo Monaco, who executed another Coronation of the Virgin, also in the Uffizi.