Cramp fasciculation syndrome (CFS) is a rare[1] peripheral nerve hyperexcitability disorder.
Most cases of cramp fasciculation syndrome are idiopathic,[3] although some research points to an autoimmune component that may be partly genetic in etiology.
[4] Cramp fasciculation syndrome is diagnosed by clinical examination and electromyography (EMG).
[8] Treatment options include anti-seizure medications such as carbamazepine, immunosuppressive drugs and plasmapheresis.
[citation needed] Carbamazepine therapy has been found to provide moderate reductions in symptoms.