Officially opened on November 5, 1985, it is now part of the Trillium Health Partners hospital group and primarily serves the communities of north Mississauga: Streetsville, Meadowvale, Erin Mills and the surrounding area.

In 2012, it was ranked as the best hospital in the Greater Toronto Area in a study conducted by the Canadian Institute for Health Information.

[3] The hospital has expanded to include a new cancer treatment centre (The Carlo Fidani Peel Regional Cancer Centre) and also a regional maternal child care program.

In addition to chemotherapy, there are six linear accelerators (radiation treatment machines).

However, GO Transit indirectly serves the hospital by stopping at the entrances from Eglinton Avenue and Erin Mills Parkway.