Cristaria plicata, the cockscomb pearl mussel, is a freshwater mussel, an aquatic bivalve mollusk in the family Unionidae.

This species is native to northeast Asia and now also present in parts of southeast Asia.

[2][1][3][4] This large mussel is listed as endangered in South Korea.

The mitochondrial genome of this species was sequenced in 2011 or 2012.

[5] In China, this species is significant as "one of the most important freshwater mussels for pearl production in the country.