Cruzeiro do Sul (Portuguese pronunciation: [kɾuˈzejɾu du ˈsuw], Southern Cross) is a municipality located on the Juruá river in the west of the Brazilian state of Acre.

The municipality contains 23% of the 846,633 hectares (2,092,080 acres) Serra do Divisor National Park, created in 1989.

[3] The principal economic activity of the municipality is rubber extraction and export, as it was in the majority of the state of Acre.

The parish was founded in 1915 by Spiritan priests, who established the first church in the Juruá valley.

With more settlers, the territory was divided in 1930 and German priests were assigned to this area of the Upper Juruá.

[7] The urban area of Cruzeiro do Sun has a size of 24.794 square kilometres (9.573 sq mi).

[8] Although the town has a tropical climate typical of Acre and the Amazon region (Köppen Am, bordering on Af as July receives just under 60 millimetres (2.4 in) of rainfall) it is notable for sporadic cold spells not typically found in low-lying equatorial areas.