Manoel Urbano (Portuguese pronunciation: [mɐnuˈɛw uʁˈbɐ̃nu]) is a municipality located in the center-western region of the Brazilian state of Acre.

The municipality contains 2% of the 750,795 hectares (1,855,250 acres) Cazumbá-Iracema Extractive Reserve, established in 2002 to support sustainable use of the natural resources by the traditional population.

[3] It also contains about 66% of the 695,303 hectares (1,718,130 acres) Chandless State Park, created in 2004, which protects an area of rainforest with bamboos that contains various endemic species of flora and fauna.

At that time supplies and produce were shipped via the Purus by boats and smaller vessels from the ports of Belém and Manaus.

[5] In 1936 the residents asked the state government to make the settlement a town named after Manoel Urbano, an Amazonian mestizo from the Manacapurú region who had explored the Purus River.