Cusae (Ancient Greek: Κοῦσαι or Κῶς; Coptic: ⲕⲱⲥⲉⲓ or ⲕⲟⲥⲉⲓ)[2] was a city in Upper Egypt.

Its Ancient Egyptian name was qjs (variant qsy), conventionally rendered Qis or Kis, with many further transliterations such as Qosia.

It was a cult centre for Hathor, and also contained a necropolis, Meir, which was used during the Middle Kingdom to hold the tombs of local aristocrats.

The bishopric of Cusae was a suffragan of the metropolitan see of Antinoë, capital of the Roman province of Thebaid I. Achilles (or Achilleus) was ordained bishop of the see by Meletius of Lycopolis.

Later bishops took the non-Chalcedonian side, the first of them being Gregorius, who assisted Pope John II (III) of Alexandria on his deathbed.