D.100 is a west-to-east state road in Turkey.

It starts at Kapıkule, the Bulgarian border check point, and ends in Gürbulak, the Iranian border check point.

[1] Running all the way from west to east, it crosses most of the north-to-south state roads, including the D.650, D.750, D.850 and D.950.

On March 10, 2017, a Sikorsky S-76 helicopter owned by Swan Aviation hit the antenna of the Endem TV Tower in heavy fog and crashed onto the State Road D100.

All seven people on board were killed.