283417320752ENSG00000177990ENSMUSG00000085576Q6NUT2P0CW70NM_173812NM_001166207NP_776173NP_001159679Dpy-19-like 2 (C. elegans) is a protein that in humans is encoded by the DPY19L2 gene.

[5] The C. elegans gene dpy-19 belongs to the dpy ("dumpy" phenotype)[6] gene class and encodes DPY-19, transmembrane protein with C-linked mannosyltransferase activity.

[7][8] In humans, it is highly expressed in testis, and is required for sperm head elongation and acrosome formation during spermatogenesis.

Mutations in this gene are associated with an infertility disorder, spermatogenic failure type 9 (SPGF9).

This article incorporates text from the United States National Library of Medicine, which is in the public domain.