[3] The mad Professor Duck Brain has stolen Yosemite Sam's Golden Cartoon Awards and is holding them for ransom.

Sam calls upon Daffy Duck to recover his awards and deal with the mad professor and his henchmen.

Many of the level names reference previous cartoon titles including The Duxorcist, Assault and Peppered and others.

Mean Machines reviewers criticised the Mega Drive version for tedious platforming, not being worth the price, having poor graphics and sounds and a close resemblance to Pink Goes to Hollywood, scoring it 53%.

[6] Computer and Video Games simply called the Mega Drive version no good with a score of 31%, but regarded the Master System version as more playable and fun, giving a fair score of 75%.