Together, they presented the Sunday night entertainment show Dan and Phil on BBC Radio 1 from January 2013 until August 2014, and the station's Internet Takeover slot from September 2014 until April 2016.

[9] He then went to the University of Manchester in 2010 to study law, but dropped out in 2011 because of a lack of interest in the subject, instead going on to pursue radio presenting and video blogging as a full-time profession.

[17] From 2019 to 2022, Howell took a hiatus from his YouTube channel, making only a handful of public appearances, such as announcing he had bought a home with Lester in January 2021,[18] while he attempted to get some projects off the ground behind the scenes.

[19] Alongside his subsequent solo tour We're All Doomed!, Howell began uploading a YouTube series called Dystopia Daily.

The 2023 revival of DanAndPhilGAMES was introduced with a comedy sketch written by Howell, "Saying Goodbye Forever," which depicted an interrupted funeral for the channel.

The show was designed to be interactive with the audience, featuring amateur music videos from listeners, challenges performed on air by the presenters, and song requests.

[38] This new show was titled The Internet Takeover, and featured Howell along with Lester live on the first Monday of every month, before coming to an end in April 2016.

[41] In 2015, Howell, along with Lester, had voice cameo appearances in the UK cinema release of Walt Disney Animation Studios' Big Hero 6 as Technician 1 & 2.

That same year, the duo also guest-starred in fellow YouTuber PJ Liguori's web series Oscar's Hotel for Fantastical Creatures, voicing anthropomorphic food items Brie and Rash.

[45] In June 2023, Howell presented a documentary titled The Cost of Being a YouTuber: UNTOLD for Channel 4, in which he interviewed creators such as Dan Rhodes and Vikkstar.

[48] The book topped the General Hardbacks Sunday Times Bestsellers list having sold 26,745 copies in the UK in the first week of its release.

[56][non-primary source needed][57] In October 2016, The Amazing Tour Is Not on Fire was released as a YouTube Red Original film by the same name along with a documentary, Dan and Phil's Story of TATINOF.

[61] Lester and Howell partnered with BBC Studios' TalentWorks to release a movie of Interactive Introverts with bonus features, such as behind the scenes content and director's commentary, on DVD, Blu-ray, and available for digital download in December 2018.

[65] Written in conjunction with psychologist Dr Heather Bolton, the book is "A practical guide to taking control of your mental health for today, tomorrow, and the days after."

Upon his return to YouTube in May 2022, Howell announced he would embark on his first solo tour titled We're All Doomed!, beginning on 10 September 2022, at the Regent Theatre, Ipswich and wrapping up at Belfast's Waterfront Hall on 3 March 2023, traveling around the UK, Europe, US, Australia and New Zealand in between.

[67][68] A ticketed live premiere of the recording was streamed via Kiswe on 15 February 2024, with a pre-show orange carpet event hosted by Lester and an after-show Q&A session with Howell.

[71] In June 2024, Lester and Howell announced their third joint tour and first since the return of their gaming channel titled Terrible Influence, which would begin that September in Antwerp.

[74] In 2014, Lester's brother, Martyn, and Howell co-founded IRL Digital, Ltd., a company that creates and sells the merchandise of various other media personalities.

[80][81][non-primary source needed] In 2019, Howell revealed that the two have been romantically involved but refrained from discussing their current relationship, stating "I'm somebody that wants to keep the details of my personal life private.