Daniel Mansuy

[1] Daniel Mansuy graduated from the École nationale supérieure de chimie de Paris (now Chimie Paris Tech) in 1967 and obtained a doctorate in science from the Université Pierre-et-Marie-Curie in 1970 under the supervision of Marc Julia.

He was co-founder in 1984 and director (1984-1996 and 1999-2005) of the Laboratory of Pharmaceutical and Toxicological Chemistry and Biochemistry at Paris Descartes University.

His work has led to the discovery of a new class of carbene and nitrene iron complexes[5] and of one of the first catalytic systems of nitrene transfer to alkanes and alkenes.

He has also developed new catalysts for the oxidation of alkanes, alkenes and aromatics, used to predict drug metabolism and in the field of pollution control.

In the field of molecular toxicology, his work has led to understand the molecular origin of drug interactions involving macrolide antibiotics such as TAO and of immunoallergic drug hepatitis due to tienilic acid.

Structure of Fe(TPP)C 2 (C 6 H 4 Cl) 2 , one of several iron carbenoid complexes prepared by Mansuy (TPP = conjugate base of tetraphenylporphyrin ). [ 4 ]