Daniels Run is a 7.82 mi (12.59 km) long 3rd order tributary to Tenmile Creek in Washington County, Pennsylvania.

According to the Geographic Names Information System, it has also been known historically as:[1] Daniels Run rises about 0.5 miles south of Glyde, Pennsylvania,[2] and then flows south to join Tenmile Creek at West Zollarsville.

[3] Daniels Run drains 17.31 square miles (44.8 km2) of area, receives about 40.3 in/year of precipitation, has a wetness index of 311.05 and is about 65% forested.

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