The high school serves fragments of two rural Pennsylvania counties.

In Northumberland County it covers the Borough of Riverside and Rush Township.

[1] Danville Area High school students may choose to attend the Columbia-Montour Area Vocational Technical School for training in the construction and mechanical trades.

The Central Susquehanna Intermediate Unit IU16 provides the school with a wide variety of services like: specialized education for disabled students; state mandated training on recognizing and reporting child abuse; speech and visual disability services; criminal background check processing for prospective employees and professional development for staff and faculty.

The Danville Area School District offers a wide variety of clubs, including forensics (speech and debate), activities and an extensive sports program.